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Index > Protein center > Cyp7a1(Gene name) > Mouse
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  • Cyp7a1 (Gene name),
  • Cholesterol 7-alpha-monooxygenase (Protein name ),  CP7A1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cyp7a1(Cyp7);
    Protein name:
    Cholesterol 7-alpha-monooxygenase;
    Alternative:
    Cholesterol 7-alpha-hydroxylase;CYPVII;Cytochrome P450 7A1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
    Subcellular Location:
    Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    503
    Sequence:
    50:
    MMSISLIWGI | AVVVSCCIWF | IIGIRRRKVG | EPPLDNGLIP | YLGCALKFGS | 
    100:
    NPLEFLRAKQ | RKHGHVFTCK | LMGKYVHFIT | NSLSYHKVLC | HGKYFDWKKF | 
    150:
    HYTTSAKAFG | HRSIDPSDGN | TTENINKTFN | KTLQGDALCS | LSEAMMQNLQ | 
    200:
    SVMRPPGLPK | SKSAVWVTEG | MYAFCYRVMF | EAGYLTLFGK | DISKTDSQRA | 
    250:
    FIQNNLDSFK | QFDQVFPALV | AGVPIHLFKT | AHKARERLAE | SLKHKNLYMR | 
    300:
    DQVSELIRLR | MFLNDTLSTF | DDMEKAKTHL | VILWASQANT | IPATFWSLFQ | 
    350:
    MIRSPEAMKA | ASEEVNGALQ | SAGQELSSGG | NAIYLDQEQL | NNLPVLDSII | 
    400:
    KEALRLSSAS | LNIRTAKEDF | TLHLEDGSYN | IRKDDIIALY | PQLMHLDPEI | 
    450:
    YPDPLTFKYD | RYLDESGKAK | TTFYRNGNKL | KYFYMPFGSG | ATICPGRLFA | 
    500:
    VQEIKQFLIL | MLSYFELELV | ESHTKCPPLD | QSRAGLGILP | PLNDIEFKYK | 
    503:
    LKH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    E1053h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    E1053r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    E1053m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    E1053p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    U1053m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    U1053p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    U1053r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    U1053h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    P1053Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Polyclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Polyclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    P1053Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Cat.:
    P1053Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Monoclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Monoclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Monoclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Monoclonal Antibody for Mouse Cholesterol 7-alpha-monooxygenase
    Protein for Mouse Cholesterol 7-alpha-monooxygenase
    Protein for Mouse Cholesterol 7-alpha-monooxygenase
    Protein for Mouse Cholesterol 7-alpha-monooxygenase
    Protein for Mouse Cholesterol 7-alpha-monooxygenase
    Protein for Mouse Cholesterol 7-alpha-monooxygenase

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Structure of the mouse cholesterol 7 alpha-hydroxylase gene."
      Tzung K.W. , Ishimura-Oka K. , Kihara S. , Oka K. , Chan L.
      Genomics21:244-247(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Liver.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "PGC-1alpha activates CYP7A1 and bile acid biosynthesis."
      Shin D.J. , Campos J.A. , Gil G. , Osborne T.F.
      J. Biol. Chem.278:50047-50052(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION BY FASTING
    5. 5.
      "Functional interaction of hepatic nuclear factor-4 and peroxisome proliferator-activated receptor-gamma coactivator 1alpha in CYP7A1 regulation is inhibited by a key lipogenic activator, sterol regulatory element-binding protein-1c."
      Ponugoti B. , Fang S. , Kemper J.K.
      Mol. Endocrinol.21:2698-2712(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY FASTING
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